Alcohol-related liver disease.~ More than 2 million Americans suffer from alcohol-related liver disease. Some drinkers develop inflammation of the liver, as a result of heavy drinking over a long period of time. Its symptoms include fever, jaundice (abnormal yellowing of the skin, eyeballs, and urine), and abdominal pain. If drinking stops, the condition may be reversible. About 10 to 20 percent of heavy drinkers develop alcoholic cirrhosis, or scarring of the liver. Although treatment for the complications of cirrhosis is available, a liver transplant may be needed for someone with life-threatening cirrhosis.