Assala was born in Damascus, Syria. She has been active since 1991. She has two children; Sham and Khaled from her first husband Ayman Al-Zahabi. They were divorced in 2005. Then she married Tarek Al-Aryan who is a famous director in 2006.
Her father Mustafa Nasry was a well known singer in Syria. He discovered her talent for singing and pushed her into the career when she was 4 years to perform children, patriotic and religious songs.
She was very attached with her father who died in 1986. It was the greatest shock in her life. She stopped singing for three years and took the role as father and mother of her younger brothers and sisters: Reem, Amani, Ayman and Ayham.