Carcinoid CANCER Zebra

I am here to bring attention to an insidious Cancer that is not very well known. CARCINOID CANCERCarcinoid tumors comprise approximately 55% of all gastrointestinal endocrine tumors. However, the overall incidence of this tumor is only 1.5 cases per 100,000 of the general population.The carcinoid syndrome occurs in less than 10% of patients with carcinoid tumors. Clinically, this syndrome develops when the vasoactive substances produced by a carcinoid tumor escape hepatic degradation and gain access into the systemic circulation. This is most commonly seen with ileal carcinoid tumors that have metastasized to the liver. Less frequent examples include carcinoid tumors with extensive retroperitoneal involvement that drain into the paravertebral venous system, or primary carcinoid tumors located outside of the GI tract (ie, bronchial or ovarian carcinoids) that do not drain into the portal venous system. The classically described primary features of the carcinoid syndrome include cutaneous flushing, bronchoconstriction, diarrhea, and right-sided cardiac valvular fibrosis. Two types of cutaneous flushing have been described. Patients with the carcinoid syndrome secondary to midgut tumors demonstrate faint pink to red flushing that begins in the face and spreads to the trunk or extremities. Patients with foregut carcinoids demonstrate a much darker, purplish flushing that involves the upper trunk and limbs. Some patients develop sensations of heat in the arms or face, and wild fluctuations in blood pressure(up or down) I edited my profile with Thomas' Myspace Editor V4.4